ANALYTICAL SERVICES
ESSENCE LINE provides complete bionalytical services essential for monitoring human and animal biomarkers, biomarker discovery and drug development. In cooperation with academic institutes, we develop original analytical methods and apply them in practise using HPLC-MS/MS, NMR, RT-PCR and microarrays.
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CNS PHARMACOGENETICS AND PHARMACOKINETICS
PHARMACOGENETICS USING MICROARRAYS
Microdialysis in rodents using certified GMO animal facility
Quantitative analysis of CNS biomarkers (LC-MS/MS, LC-MS QTOF, LC-UV, LC-ECD, NMR, qPCR, microarray)
Routine HPLC-MS/MS analysis of neurotransmitters (dopamine, DOPAC, HVA, 3-MT, serotonin, 5-HIAA, norepinephrine, GABA, glutamate from microdialysis sample or brain tissue) and ROS biomarkers (leukotriens, prostaglandins, aldehydes)
SUPPLIES OF CHEMICALS
Fine chemicals, intermediates, reagents, analytical standars
Original Technology Development
Scale Up
Industrial Supplies
ANIMAL CARE – SCREENING OF TOXINS
Elementary Analysis using XRF
Screening of Plant toxins using HPLC-MS and NMR
Complete toxin fingerprint
including the most common equine toxic plants (Ragweed, Yew, Ranunculi, Tansy, Monkshood, Dwale, HerbParis (Paris quadrifoliaL.))
MICROARRAY QUALITY INSPECTION
Spot quality inspection using AFM
Homogeneity
Complete/partial spot absence
DNA aggregation and “donut-shaping”
morphological organization on nano-level
deposition of biomolecules (clustering, accretion, pooling)co-funded by EUREKA, European funding and support programme for SME research and development
MEDICAL APPLICATIONS
Prenatal Diagnostics
Cancer Diagnostics
Metabolomics