About us

About ESSENCE LINE, s.r.o.

ESSENCE LINE, s.r.o. is a Czech biotechnology company with more than 24 years of experience in applied research, diagnostics and development of advanced analytical solutions. The company focuses on personalized medicine, molecular diagnostics, environmental safety and translational biotechnology.

What we do

The company combines scientific expertise with practical clinical and industrial applications and translates research outputs into real diagnostic, healthcare and industrial solutions.

Company profile

Reliable place for complex but meaningful diagnosis

ESSENCE LINE is a Czech biotechnology company connecting applied research, diagnostics and advanced analytical technologies with practical clinical and industrial applications.

Key facts
  • More than 24 years of applied research, development and diagnostics
  • Connection of scientific expertise with clinical and industrial use
  • Focus on personalized medicine, molecular diagnostics and environmental safety
  • Translation of research outputs into practical diagnostic solutions

Why choose us

  • More than 24 years of experience in applied research, development and diagnostics.
  • Own technology infrastructure for molecular, biochemical and analytical services.
  • Strong connection between personalized medicine, biomarkers, toxicology and environmental safety.
  • Ability to translate academic expertise into practical clinical and commercial solutions.

Partners and cooperation

  • Research centres and universities
  • Pharmaceutical companies
  • CRO partners
  • Clinical and laboratory teams
  • Industrial and technology partners
Main activity domains

From molecular diagnostics to translational biotechnology

The portfolio is organized into four connected domains that support clinical, research and industrial use.

Genetics and personalized medicine

Pharmacogenomics, carrier screening, precision diagnostics and microbiome interpretation for individualized prevention and care.

Inflammatory processes and metabolomics

Screening of inflammatory, neurodegenerative, metabolic, stress and exposure-related biomarkers.

Environmental and toxicological testing

Genotoxicity, endocrine disruption, cytotoxicity and molecular analyses for environmental and biomedical use.

Technology and research infrastructure

Microarrays, biochips, NGS, qPCR and LC-MS/MS platforms supporting precise molecular and biochemical analysis.

Main activity areas

Biotechnology, diagnostics and applied research

Genetics and Personalized Medicine

Advanced genomic and molecular diagnostic services aimed at improving individualized healthcare and preventive medicine.

  • Pharmacogenomics and prediction of individual drug response profiles.
  • Preconception genetic screening and carrier assessment.
  • Analysis of intestinal, oral and skin microbiomes.
  • Precision diagnostics and molecular biomarkers.

Inflammatory Processes, Biomarkers and Metabolomics

Identification and quantification of biomarkers associated with chronic inflammation, neurodegeneration, metabolic dysregulation and infectious diseases.

  • Inflammatory and neurodegenerative markers.
  • Vitamin and energy metabolites including NAD+/NADH.
  • Klotho protein, stress hormones and endocrine metabolites.
  • Monitoring of pharmaceuticals, xenobiotics and exposure biomarkers.

Environmental and Toxicological Testing

Advanced toxicological and environmental safety assessments for industrial, biomedical and research applications.

  • Genotoxicity testing – evaluation of DNA-damaging potential.
  • Endocrine disruption assessment – compounds interfering with hormonal signaling.
  • Cytotoxicity testing – toxic cellular effects and biological compatibility.
  • Environmental and exposure-related molecular analyses.

Advanced Technologies and Research Infrastructure

Modern technological infrastructure enabling high-throughput and high-sensitivity molecular and biochemical analyses.

  • Microarray and biochip technologies including DNA and protein microarrays.
  • Compatibility with Affymetrix, Illumina, Agilent and other platforms.
  • Nanopore sequencing, qPCR and molecular assay development.
  • LC-MS/MS and highly sensitive targeted and untargeted molecular analysis.
Technology & Projects

Research, Development and Innovation

ESSENCE LINE actively participates in national and international research and innovation projects focused on precision medicine, neurodegenerative disorders, molecular diagnostics, biochip and microfluidic technologies, AI-assisted interpretation of genomic and metabolomic data and translational biotechnology applications.

Current research orientation includes precision medicine, neurodegenerative disorders, molecular diagnostics, biochip technologies and AI-assisted interpretation of genomic and metabolomic data.

Advanced infrastructure

Technologies for high-sensitivity analysis

  • Microarray and biochip technologies
  • NGS, Nanopore sequencing and qPCR
  • LC-MS/MS analytical chemistry
  • Multiplex analytical panels
Careers and cooperation

Cooperation and Careers

We believe that science should have a real practical impact.

If you are interested in professional cooperation, laboratory partnership or joining our projects, please contact us.

Contact us
Portfolio contact

Diagnostics for clients, clinics and partners

Contact us for home diagnostics, clinical cooperation, partner implementation or custom testing.

Contact page
Contact

We are ready to help

Radiová 1285/7, 102 00 Prague 10 – Hostivař, Czech Republic

info@essenceline.cz

+420 273 130 999

Contact page
Essence Line laboratory